Sentinel Bio's Joshua Monrad on why DNA synthesis is the one clean choke point for stopping an engineered pandemic: "The reason we talk about securing it is that it seems like an unusually good choke point for preventing AI-enabled biotechnology misuse. It's a physical product with a pretty complicated production process. It's not something shared as easily as the weights of an open-source model, or any model for that matter." "It's also something with a really high signal-to-noise ratio. The…