White Pill Wednesday: the first mRNA cancer vaccine just cleared Phase 3. • Given after surgery alongside Keytruda, it significantly improved recurrence-free survival in patients with completely resected stage 2B to 4 melanoma • How it works: sequence the DNA of your tumor, identify the mutations unique to your cancer, and manufacture a personalized mRNA shot that trains your immune system to hunt cells carrying those markers • It's the first positive Phase 3 for an individualized neoantigen…

MTS@MTSliveAug 19

SITUATION DETECTED: A personalized Moderna-Merck mRNA cancer vaccine has succeeded in a Phase 3 melanoma trial, the first late-stage win for an individualized mRNA cancer therapy. The companies announced the result today, and Moderna’s stock surged about 90% on the news.